KMID : 1098420160240030222
|
|
Korean Journal of Medicinal Crop Science 2016 Volume.24 No. 3 p.222 ~ p.227
|
|
Antioxidant and ¥á-Glucosidase Inhibitory Activities of Tradescantia pallida (Rose) Hunt Leaf Extract and Fractions
|
|
Kim Ju-Sung
Kim Kyeoung-Cheol
|
|
Abstract
|
|
|
Background: The biological activities of Tradescantia pallida grown in Korea have not been well determined, thus the aim of this study was to investigate the possibility of using it as a medicinal plant.
Methods and Results: To investigate the antioxidant activity, ¥á-glucosidase inhibitory effect and antimicrobial activity of T. pallida, we performed the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and reducing power assay. This assay for T. pallida leaf extract showed the highest antioxidant activity for the ethyl acetate fraction (RC50= 14.55 ¡¾ 0.16§¶/§¢ and Abs = 0.613 at 300§¶). Further, the ethyl acetate fraction exhibited higher ¥á-glucosidase inhibitory effect with an IC50 value of 14.1 ¡¾ 0.1§¶/§¢ and showed antimicrobial activity against gram positive bacteria (minimum inhibitory concentration = 1,000§¶/§¢).
Conclusions: The ethyl acetate fraction of the crude methanol extract of T. pallida showed remarkable antioxidant activity, ¥á-glucosidase inhibitory effects and antimicrobial activity. These activities might be related to the flavonoid content in the T. pallida leaf extract.
|
|
KEYWORD
|
|
Setcreasea pallida, Tradescantia pallida, Antioxidant Activity, Antimicrobial Activity, ¥á-Glucosidase Inhibitory Effect
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|